WebMay 29, 2024 · PCa is the fifth leading cause of cancer death in men worldwide. The development and progression of PCa is typically associated with an inflammatory microenvironment [].The involvement of CCL2-CCR2 axis in PCa progression has been consistently observed in many studies, including an enhanced CCL2-CCR2 signaling … WebThe CCR2 RFP/+ knock-in mice are a powerful tool for short-term tracking of monocytes, but if infiltrating monocytes stop expressing the CCR2 marker after in situ reprogramming as reported in a sterile liver injury model , they will “disappear” in the CCR2 RFP/+ mouse brain tissue. Furthermore, although parabiosis and BM chimera are used in ...
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