Cd44-slc1a2 gene fusions in gastric cancer

Author: bfmm

August undefined, 2024

WebFeb 2, 2016 · CD44-SLC1A2 silencing also significantly reduced intracellular glutamate levels and sensitized SNU16 cells to cisplatin. Fusions of SLC1A2 to upstream CD44 … WebNotably, several studies have reported SLC1A2, a glutamate transporter, as a common 3' partner gene for fusions in solid tumors. For example, CD44- SLC1A2 fusion is found in both...

Novel fusion transcripts in human gastric cancer revealed by ...

WebCD44-SLC1A2 gene fusions in gastric cancer. - CORE Reader. We are not allowed to display external PDFs yet. You will be redirected to the full text document in the … WebCD44-SLC1A2 silencing caused significant reductions in intracellular glutamate concentrations and sensitized SNU16 cells to cisplatin, a commonly used … hijrah itu sunnah

CD44-SLC1A2 Fusion Transcripts in Primary Colorectal Cancer

WebApr 6, 2011 · A newly discovered hybrid gene appears to play a direct role in some stomach cancers, according to an international team of scientists led by researchers at Duke-NUS Graduate Medical School. The hybrid gene is a fusion of two separate genes, and is one of the first described in gastric cancer, which is the most lethal malignancy … WebApr 1, 2011 · SLC1A2 undergoes a genomic breakpoint in its 5 0 region and forms a fusion gene with CD44 in gastric and colorectal cancers (Tao et al., 2011;Shinmura et al., … Webdiagnostic tools for gastric cancer. "This is an extremely exciting area, as it opens up a potential role for ... CD44-SLC1A2, where the fusion gene contributes actively to the hijrah itu pengorbanan

New fusion gene plays role in some stomach cancers

CD44-SLC1A2 gene fusions in gastric cancer. - CORE Reader

WebCD44-SLC1A2 gene fusions in gastric cancer Jiong Tao, Nian Tao Deng, Kalpana Ramnarayanan, Baohua Huang, Hue Kian Oh, Siew Hong Leong, Seong Soo Lim, Iain … WebThe results suggest that the expression of SLC1A2 fusion transcripts is related to a subset of primary CRCs and may contribute to the elucidation of the characteristics of S LC1A 2 fusion-positive CRCs in the future. A CD44-SLC1A2 fusion has recently been discovered in a subset of primary gastric cancers, and an APIP-SLC1A2 fusion has been … hijrah itu pengorbanan lirikWebDec 13, 2014 · Importantly, several fusion genes, DUS4L–BCAP29 [ 19 ], CD44-SLC1A2 [ 20] have been reported in gastric cancer in western country. In our study, 3 chimeric transcripts were supported by the two detection methods (Table 4 ). Among them, CBX3-C15orf57 was detected in healthy human beings before [ 25 ]. hijrah itu berat

"WebOct 25, 2024 · For example, CD44-SLC1A2 fusion is found in both gastric 7 and colorectal cancers 22. ... Tao, J. et al. CD44-SLC1A2 gene fusions in gastric cancer. Sci. Transl. Med 3, 77ra30 (2011). " - Cd44-slc1a2 gene fusions in gastric cancer

Cd44-slc1a2 gene fusions in gastric cancer

WebIn primary tumors, CD44-SLC1A2 gene fusions were detected in 1 to 2% of gastric cancers, but not in adjacent matched normal gastric tissues. When we specifically silenced CD44-SLC1A2, cellular proliferation, invasion, and anchorage-independent growth were … WebCD44-SLC1A2 gene fusions in gastric cancer. Tao J. , Deng N.T. , Ramnarayanan K. , Huang B. , Oh H.K. , Leong S.H. , Lim S.S. , Tan I.B. , Ooi C.H. , Wu J. , Lee M. , Zhang …

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WebClassical cytogenetic approaches have revealed many of the chromosomal aberrations that may occur in gastric cancers (GC), although few alterations of specific genes have been identified so far. Gene... WebCD44-SLC1A2 gene fusions in gastric cancer. Jiong Tao, Nian Tao Deng, Kalpana Ramnarayanan, Baohua Huang, Hue Kian Oh, Siew Hong Leong, Seong Soo Lim, Iain …

WebJan 10, 2015 · A CD44-SLC1A2 fusion has recently been discovered in a subset of primary gastric cancers, and an APIP-SLC1A2 fusion has been described in a colon cancer … WebIntroduction. Lung cancer includes two major histological groups, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Lung adenocarcinoma (LUAD) is a histological subtype of NSCLC, accounting for about 50% of all lung cancer cases. 1 LUAD is the most common cancer in both men and women, and it is also the leading cause of …

WebTitle: CD44-SLC1A2 gene fusions in gastric cancer: Authors: Tao, J. Deng, N.T. Ramnarayanan, K. Huang, B. Oh, H.K. Leong, S.H. Lim, S.S. Tan, I.B. Ooi, C.H. WebApr 25, 2013 · The structure of the known gastric cancer gene fusion CD44/SLC1A2 is depicted for comparison (right panel). An internal start codon within exon 2 of SLC1A2 is …

WebIn primary tumors, CD44-SLC1A2 gene fusions were detected in 1 to 2% of gastric cancers, but not in adjacent matched normal gastric tissues. When we specifically silenced CD44 …

Webi ACKNOWLEDGEMENT I am extremely grateful and indebted to my supervisor Associate Professor Patrick Tan and my co-supervisor Dr. Celestial Yap for their advice and … ez outsWebCD44-SLC1A2 gene fusions in gastric cancer Jiong Tao, Nian Tao Deng, Kalpana Ramnarayanan, Baohua Huang, Hue Kian Oh, Siew Hong Leong, Seong Soo Lim, Iain Beehuat Tan, Chia Huey Ooi, Jeanie Wu, Minghui Lee, Shenli Zhang, Sun Young Rha , Hyun Cheol Chung , Duane T. Smoot, Hassan Ashktorab, Oi Lian Kon, Valere Cacheux, … ez out bail bonds nevadaWebTao J., et al., CD44-SLC1A2 Gene Fusions in Gastric Cancer. Science Translational Medicine. 3(77):77ra30 (2011) Testimonials. I am impressed with the fast and friendly response from both the technical and administrative staff. The lead time to completion of sequencing is pleasantly short. [HiSeq WGS Sequencing] (Dr. Ng Sock Hoon, Research ... ez outletsWebCD44-SLC1A2 gene fusions in gastric cancer. - CORE Reader. We are not allowed to display external PDFs yet. You will be redirected to the full text document in the repository in a few seconds, if not click here. ez out skeletonWebOct 25, 2024 · Despite a trend for the prevalence of gene fusions in young cancer patients, no studies have systematically investigated novel fusions in young patients with DGCs due to the relative rarity of early-onset gastric cancer, which is notable for its strong enrichment of diffuse histology. ... For example, CD44-SLC1A2 fusion is found in both gastric ... hijrah itu satu pengorbanan hijrah itu perjuangan lirikWebMay 17, 2024 · Background Cancer stem cells (CSCs), drug-resistant cancer cell subsets, are known to be responsible for tumor metastasis and relapse. The JAK/STAT pathway, activated by SH2 domain, is known to regulate the tumor growth in gastric cancer (GC). Now, this study was designed to examine whether BMX-ARHGAP affects the GC stem … ez out sizes