Cisplatin pubchem

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August undefined, 2024

WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. Unfortunately, the mechanism for cisplatin ... WebJun 15, 2024 · Keywords: 3-MethylAdenine (3-MA) (PubChem CID: 1673); 5-Fluorouracil (5-FU) (PubChem CID: 3385); Allicin (PubChem CID: 65036); Apatinib (PubChem CID: 45139106); Arsenic trioxide (As (2)O (3)) (PubChem CID: 14888); Autophagy; Bafilomycin A1 (PubChem CID: 6436223); Bortezomib (PubChem CID: 387447); Brefeldin A …

Methylseleninic acid promotes antitumour effects via nuclear …

WebSep 5, 2014 · A single injection of cisplatin (20mg/kg; i.p) induced nephrotoxicity, 5-HT3 antagonists (tropisetron, granisetron and ondansetron,) were given twice daily for 3 day (3mg/kg; i.p). Finally animals were euthanized and blood sample was collected to measure urea and creatinin level. WebJul 12, 2024 · Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in … marriage license washington state copy

DT-13 synergistically potentiates the sensitivity of gastric cancer ...

WebThe chemotherapeutic cisplatin causes renal dysfunction and renal proximal tubular cell (RPTC) apoptosis. The goal of these studies was to examine the role of p53, caspase 3, 8, and 9, and mitochondria in the signaling of cisplatin-induced apoptosis. Cisplatin (50 microM) produced time-dependent apo … WebFeb 17, 2016 · Keywords: Atropine (PubChem CID: 174174); Carbachol (PubChem CID: 5831); Cisplatin (PubChem CID: 2767); Esophageal smooth muscle cells; GR113808 (PubChem CID: 119376); Gastric emptying; Gastro-intestinal system; Gastrointestinal transit; L-NNA (PubChem CID: 440005); Lonicerae Japonicae Thunberg; Loperamide … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … marriage license waukesha county

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WebDec 15, 2016 · DOI: 10.1016/j.bcp.2016.09.022 Abstract Salinomycin, a polyether antibiotic, acts as a highly selective potassium ionophore and has anticancer activity on various cancer cell lines. Cisplatin has been proved as chemotherapy drug for advanced human non-small cell lung cancer (NSCLC). WebWe present MSA as a promising chemotherapeutic agent with synergistic antiproliferative effects with cisplatin. Keywords: Akt; Cisplatin; Cisplatin (PubChem CID: 441203); FOXO; LY294002 (PubChem CID: 3973); Methylseleninic acid; Methylseleninic acid (PubChem CID: 161597); PI3K; Selenium; Sodium selenite (PubChem CID: 24934). nbc universal sheriff substationWebHerbal medicine has attracted great attention in the recent years and is increasingly used as alternatives to chemical drugs. Several lines of evidence support the positive impact of medicinal plants in the prevention and cure of a wide range of diseases. Thymoquinone (TQ) is the most abundant const … marriage license washington state kitsap

"WebDimethylsulfoxid hat entzündungshemmende ( antiphlogistische) und schmerzlindernde ( analgetische) Eigenschaften. [8] [20] Es findet daher therapeutische Verwendung als perkutanes (lat. durch die Haut) Arzneimittel zur Behandlung lokaler Schmerzzustände (beispielsweise bei Sportverletzungen oder rheumatischen Beschwerden). " - Cisplatin pubchem

Cisplatin pubchem

FoxO-1 contributes to the efficacy of the combination of the XPO1 ...

WebAdriamycin (PubChem CID: 31703); Anti-inflammatory agent; Cisplatin (PubChem CID: 84691); Cyclophosphamide (PubChem CID: 2907); Cyclosporine A (PubChem CID: 5284373); Fibrosis; Gemcitabine (PubChem CID: 60750); Mitoxantrone (PubChem CID: 4212); Review; Romidepsin (PubChem CID: 5352062); Tamoxifen (PubChem CID: … WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the …

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WebChemical Name. cis-Diaminodichloroplatinum. Biological Activity. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis. WebC2210000 Cisplatin European Pharmacopoeia (EP) Reference Standard Synonym (s): cis-Diammineplatinum (II) dichloride, cis-Dichlorodiammine platinum (II), cis-Platinum (II) diammine dichloride, Cisplatin Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 Molecular Weight: 300.05 EC Number: 239-733-8 MDL number: MFCD00011623 …

WebCisplatin is approved to be used alone or with other drugs to treat: Bladder cancer. It is used alone in patients with advanced cancer that cannot be treated with other therapies, … Webazane;dichloroplatinum Cl2H6N2Pt - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 503 National Center for Biotechnology Information 8600 Rockville Pike, …

WebPurpose: Cisplatin resistance is a major concern in ovarian cancer treatment. The aim of this study was to investigate if wedelolactone could perform better in resistant ovarian cancer cells when used in combination with cisplatin. Methods: Growth inhibitory potential of wedelolactone and cisplatin was investigated through MTT reduction assay ... WebJan 5, 2024 · Keywords: 5-Fluorouracil (PubChem CID: 3385); Carboplatin (PubChem CID: 38904); Cell cycle arrest; Cisplatin (PubChem CID: 441203); DT-13; DT-13 (PubChem CID: 101514160); Drug combination; Gastric cancer cell; Paclitaxel (PubChem CID: 36314); Topotecan (PubChem CID: 60700); Topotecan (TPT). Copyright © 2024 Elsevier B.V. …

WebCisplatin is one of the most emetogenic chemotherapy agents, but this is managed with prophylactic antiemetics (e.g. ondansetron, granisetron, etc.) in combination with …

WebCisplatin(CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts. MedChem Express, HY-17394: DNA alkylator/crosslinker MedChem Express HY-17394: Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of ... marriage license whatcom countyWebCisplatin Cl2H6N2Pt CID 5460033 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. marriage license wichita falls txWebAug 20, 2024 · When administered with cisplatin, MAP30 produced a synergistic effect on cisplatin-induced cell cytotoxicity in ovarian cancer cells. When low doses of cisplatin … marriage license williamson county texasWebAnastrozole C17H19N5 CID 2187 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. This application requires Javascript. Please turn on Javascript in order to use this application. marriage license youngstown ohioWebTaken together, our results support FoxO-1 as one of the key factors promoting sensitivity towards selinexor and the synergistic interaction between cisplatin and selinexor in ovarian carcinoma cells with selected molecular backgrounds, highlighting the need for treatment regimens tailored to the molecular tumor features. Keywords: marriage license with immigrantsWebJan 1, 2024 · Cisplatin atau sisplatin merupakan obat kemoterapi berbasis platinum yang digunakan untuk terapi kanker, seperti kanker ovarium, testis, dan kandung kemih. Cisplatin adalah salah satu obat antikanker yang paling banyak digunakan karena efikasinya yang luas untuk terapi berbagai jenis kanker. marriage license york county paWebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. nbc universal shows