Haptotactic response
WebB-cell receptors (BCRs) recognize unique antigens, and BCR signaling is critical for the humoral immune response (32). BCR signaling interacts with both the chemokine and LFA-1 signaling networks through downstream proteins such as ZAP70 and p66Shc, orchestrating B-cell development and migration responses (4, 10, 33). WebNov 1, 1995 · Haptotactic response/chemotactic (1 haptotactic) response ratio. c. Migration was assessed using fibronectin-coated filters as described. under “Experimental Procedures.” Results, at the net ...
Haptotactic response
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WebDec 14, 2024 · Critical to cell guidance and development, haptotaxis is directional cell movement in response to an adhesive substrate, and a method has been developed … WebThe haptotactic effect is treated by the receptorkinetic model, and the cell random walk is characterized macroscopically as cell diffusion. Finally, the values of cell …
WebCONCLUSION: These results demonstrate for the first time that tumor-specific alphavbeta3 contributes to spontaneous metastasis of breast tumors to bone and suggest a critical role for this receptor in mediating chemotactic and haptotactic migration towards bone factors. DOI: 10.1186/bcr1398: Alternate Journal: Breast Cancer Res. PubMed ID: 16608535 http://npi.ucla.edu/cousins/publication/tumor-specific-expression-alphavbeta3-integrin-promotes-spontaneous-metastasis
WebJul 1, 2009 · Silencing smad-2 signaling blocks PMC haptotaxis in response to TGF-β1. Haptotactic migration of PMC was evaluated with and without TGF-β1. PMC showed a significantly increased haptotactic activity with TGF-β1 compared with BSA control. Optimum haptotaxis of PMC was noted at a dose of 5 ng of TGF-β1 (Fig. 9A). PMC … WebMay 1, 1984 · The stimulation of migration occurred over a concentration range of 1-100 micrograms/ml of laminin or fibronectin, with a peak response occurring between 12.5 and 25 micrograms/ml.
WebIn 3D collagen gels with FN gradients, Mena expression also induced a strong haptotactic response (Fig1D), independently of velocity . While the exact concentration of FN in tumors is unknown, FN is expressed by tumor and stromal cells, and accumulates in the perivascular area via leakage from the bloodstream, where FN levels as high as 400μg ...
WebNov 15, 2006 · Here, we found that treatment with recombinant human BMP-2 (rhBMP-2) enhanced the haptotactic response of murine osteoblastic MC3T3-E1 and … maryland icc tollsWebMar 1, 2000 · MCP-1 mediated haptotactic activity in PMCs. PMCs demonstrated haptotactic response to MCP-1 in a concentration-dependent manner. Maximum activity was noticed at 50 ng/ml of MCP-1 (Table1); the activity plateaued thereafter. To assess the effect of cytokines and endotoxin, the cells were pretreated with IL-2 or LPS and tested … maryland ice cream trucksWebIt has been reported that B-cell chemotaxis in response to higher chemokine doses showed an increasing trend of individual cells exhibiting chemorepulsion rather than chemotaxis … husband romantic quotesWebJul 1, 2009 · Haptotaxis is defined as the movement of cells in response to a dose-dependent gradient of substratum-bound cytokine. PMC were found to respond with … husband role in a marriageWebNov 7, 2016 · Microfluidic system to probe chemotactic and haptotactic migration at the single cell level. To quantitatively track immune cell migration in simultaneous response to chemotactic and haptotactic ... husband romantic anniversary cakeWebApr 1, 2013 · Haptotaxis (ie, cell movement in response to gradients immobilized on a substratum) is distinct from chemotaxis, which is defined as cell migration along a … maryland ibcWebJun 1, 2009 · Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF- 1 in vitro June 2009 AJP Lung Cellular and Molecular … husband role in marriage