Nejm hypothermia article
WebNov 24, 2024 · Most of the patients who die after cardiac arrest do so because of hypoxic-ischemic brain injury (HIBI). Experimental evidence shows that temperature control targeted at hypothermia mitigates HIBI. In 2002, one randomized trial and one quasi-randomized trial showed that temperature control targeted at 32–34 °C improved neurological … WebJan 26, 2024 · Among the 257 patients who had a VABS-II score of at least 70 before cardiac arrest and who could be evaluated, the rate of the primary efficacy outcome did not differ significantly between the hypothermia group and the normothermia group (36% [48 of 133 patients] and 39% [48 of 124 patients], respectively; relative risk, 0.92; 95% …
Nejm hypothermia article
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WebMay 21, 2007 · The hypothermia After Cardiac Arrest Study Group. Mild Therapeutic Hypothermia To Improve Neurologic Outcome After Cardiac Arrest. NEJM 2002 346;8:549-56. Major Finding. For survivors of witnessed out-of-hospital cardiac arrests, 24 hours of therapeutic hypothermia improved both mortality (NNT 7), and morbidity (NNT 6 for …
WebDec 29, 1994 · Accidental hypothermia is defined as an unintentional decline in the core temperature below 35 °C. At this temperature, the coordinated systems responsible for … WebJun 17, 2024 · In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not lead to a lower incidence of death by 6 months than targeted …
Web1 day ago · Original Article Apr 13, 2024. Dersimelagon in Erythropoietic Protoporphyrias. M. Balwani and Others. Patients with erythropoietic protoporphyria or X-linked … WebJun 16, 2024 · Nearly 2 decades ago, the concept of “therapeutic hypothermia” was introduced into the care of patients with coma after cardiac arrest (NEJM JW Gen Med …
WebNov 17, 2013 · Methods. In an international trial, we randomly assigned 950 unconscious adults after out-of-hospital cardiac arrest of presumed cardiac cause to targeted …
WebAug 3, 2024 · Therapeutic hypothermia did not reduce the combined outcome of death or disability at 18 months after neonatal encephalopathy in low-income and middle-income countries, but significantly increased death alone. Therapeutic hypothermia should not be offered as treatment for neonatal encephalopathy in low-income and middle-income … luton new homesWebHypothermia is classified into mild (core temperature of 34°C–36°C), moderate (core temperature of 30°C–33°C), and severe (core temperature less than 30°C) hypothermia. 3. If possible, body temperature should be checked, preferably by rectal thermometer, while in the wilderness setting, as this may help classify and guide treatment. jdm air freshenerWebWhole-body hypothermia reduces the risk of death or disability in infants with moderate or severe hypoxic–ischemic encephalopathy. Among term infants, hypoxic–ischemic … luton news deathsWebThis hypothesized absolute 15% increase in favorable neurologic outcomes was based on a 46% improvement of favorable outcomes (relative risk, 1.46; 95% CI, 1.12-1.92; P = .006) with hypothermia in a 2007 meta-analysis 7 and on a 50% increase (P = .02) in favorable outcomes in a subgroup of patients with severe traumatic brain injury who were younger … jdm ap1 headlightsWebOf the 1747 patients in whom the functional outcome was assessed, 488 of 881 (55%) in the hypothermia group had moderately severe disability or worse (modified Rankin scale … luton nottingham forestWebJun 16, 2024 · In an open-label, blinded-outcome-assessor trial, Dankiewicz et al. randomly assigned 1900 adults with coma who had had an out-of-hospital cardiac arrest of … luton officeWebHowever, clinical trials have found that therapeutic hypothermia leads to worse survival outcomes for other conditions, such as traumatic brain injury 21,22 and bacterial meningitis. 23 To date, the only randomized trials to examine therapeutic hypothermia vs no temperature management have been for out-of-hospital cardiac arrest. 2,3 In-hospital … jdm battery cover